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The girl's name Guadalupe \gu(a)-dalu-pe, guad(a)-lupe\ is pronounced gwah-da-LOO-pay. It is of Spanish origin, and its meaning is "wolf valley". Refers to Mary as Mexico's "Our Lady of Guadalupe". For more information, see also the related name Lupita. Guadalupe is a very popular female first name and a very popular surname (source: 1990 U.S. Census). Displayed below is the baby name popularity trend for the girl's name Guadalupe. Compare Guadalupe with related baby names.
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