Meaning and name origin
Prescilla \pr(es)-cilla, pres(cil)-la\ as a girl's name is of Latin origin, and the meaning of Prescilla is "ancient, venerable". Prescilla is a variant of Priscilla (Latin); biblical: a first-century Christian missionary. Not regularly used as a birth name for girls.
Prescilla is not a popular first name for females and an equally uncommon surname or last name for all people (Source: 2000 U.S. Population Census).
Displayed below is a comparison of the popularity of the girl name Prescilla and its variant forms. The only popular variation form ranked in the Top 1000/100 is Priscilla (#484). (Source: 2014 Birth Name Statistics).