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The girl's name Sissie \s(is)-sie\ is a variant of Cecilia (Latin) and Sissy, and the meaning of Sissie is "blind one". The baby name Sissie sounds like Cissie and Sissee. Other similar baby names are Lissie, Kissie and Missie. Sissie is an uncommon first name for women and an equally uncommon last name for both men and women. (1990 U.S. Census) Displayed below is the baby name popularity trend for the girl name Sissie. Compare Sissie with its source forms and related girl names.
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