What does Keyes mean?
Keyes \ke-yes\ as a boys' name is of Old English origin. Probably an occupational name to do with the possession of keys. Also possibly from Kay "happy". Francis Scott Key, author of "The Star-Spangled Banner".
Keyes is an uncommon given name for men but a very popular last name for all people (#2079 out of 150436, Top 1%). (2000 U.S. Census)
Kai (#177 a year ago) and Kay are the popular related forms of Keyes (#unlisted). These boy names are at the apex of their popularity today (usage of 0.4115%), except for the version Kay which has become less stylish. Kai (#177) is the most contemporarily stylish boy name here. Shown below is an analysis of the usage of the boy name Keyes and affiliated names. (Top 1000 Baby Names Records, 2014)