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The boy's name McGwire \m-cgwi-re, mc(g)-wire\ is a variant of Maguire (Irish, Gaelic), and the meaning of McGwire is "son of the beige one". The baby name McGwire sounds like McGuire and MacGuire. McGwire is an uncommon first name for men and an equally uncommon last name for both men and women. (1990 U.S. Census) Displayed below is the baby name popularity trend for the boy name McGwire. Compare McGwire with its source form and related boy names.
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