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The boy's name O'Keefe \o(')-kee-fe\ is a variant of O- (Irish), and the meaning of O'Keefe is "descendant of". Similar baby names are Keefe and Keeffe. O'Keefe is an uncommon first name for men and an equally uncommon last name for both men and women. (1990 U.S. Census) Displayed below is the baby name popularity trend for the boy name O'Keefe. Compare O'Keefe with its source form and related boy names.
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| O'Keefe - meaning of O'Keefe name © 2009 Thinkbabynames.com, a Baby Names company. | |||||