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The boy's name Onofrio \o-nof-rio, on(o)-frio\ is of Italian and German origin, and its meaning is "defender of peace". Actor Vincent D'Onofrio. Onofrio has 3 variant forms: Onofre, Onofrius and Onophrio. For more information, see also the related name Humphrey. Baby names that sound like Onofrio are Onofredo, Onfroi and Onfre. Onofrio is a very rare male first name and a very popular surname (source: 1990 U.S. Census). Displayed below is the baby name popularity trend for the boy's name Onofrio. Click here to compare Onofrio with related baby names.
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