What does Sixtus mean?
Sixtus is an uncommonly occurring first name for males and also an uncommon surname for both adults and children. (2000 U.S. Census)
The only prominent related form of Sixtus (#unlisted) ranked in the Top 1000 is Sixto. These boy names reached the height of their popularity during 1940-1949 (usage of 0.054%) and are now less popular. Below is a graphed comparison of the usage of Sixtus and related names. (2014 Birth Statistics)